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I need fucking drugs
Replies: >>25260 >>25265
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>need fucking drugs
So your dick stopped working?
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>>25258 (OP) 
i can offer some weed
poppers
Replies: >>25263
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>>25262
hehehe
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>>25258 (OP) 
Replies: >>25266 >>25271
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>>25265
Do mushrooms and kick away that nasty DXM habit…
Replies: >>25267 >>25269
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>>25266
hi furfagmaster how does the schroom goes
Replies: >>25268
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>>25267
I still need the induction coil sterilizer to come in before I can proceed. Otherwise I’m just germinating spores on agar plates at the moment.
>>25266
you know it's really not a good idea for people that aren't mentally healthy to do psychedelics right
Replies: >>25270 >>25303
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>>25269
ah what could happen c:
>>25265
where do u get ur research chemicals and weeed
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You can also buy agar plates that are already isolated and colonized to make the growing process easier. Starting out from spores is a huge fucking pain tbh; I still like using spores though because they’re good for storage long-term.
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Replies: >>25275
>>25274
wtf
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i don't eat ass
Replies: >>25279
>>25276
I posted a pic of you making out with my ass
Replies: >>25280
>>25279
how big is your beyblade collection
Replies: >>25281
>>25280
I don't have any I will never have any
Replies: >>25282
>>25281
how big is your bunny
Replies: >>25283
>>25282
die freak
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so no bunny
Replies: >>25285
>>25284
shut up
none of you care about me and I don't have to share anything with you retards
Replies: >>25289
>>25287
relax shinji
Replies: >>25291
>>25289
you're the one interrogating me
Replies: >>25292
>>25291
the first question was a joke and the second was just about the size of your bunny lol
Replies: >>25294
>>25292
you don't want to know you just want to use me
Replies: >>25295
>>25294
i'm literally just talking to you
what would i even use you for
Replies: >>25296
>>25295
why would you want to talk to me
Replies: >>25298
>>25296
why have i continued to reply to you for the last how many years
Replies: >>25299
>>25298
because you're a loser dumb idiot
>>25269
It's literally the most effective treatment by a country mile
Truly you fit the phrase "miserable gaping hole of an existence"
Replies: >>25306
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I need fucking hugs
Replies: >>25307
>>25303
wow proof?
Replies: >>25308 >>25337
>>25304
cute
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>>25306
>wow proof?
I mean this reply is pretty good proof of the kind of disingenuous bullshit and total lack of interest in scholarship or other's-and-your-own wellbeing that you're constantly putting out.
With regards to the shrooms, there's a fair number of studies for how hard it is to get permission to do them, but you'd have to give discreet cases to get specific examples.
Addiction and depression are two of the most widely established, the former of which I think it's reasonable to say might be an issue for wish and the latter of which he's literally on medication for.
>wow proof?
Literal top results:
"psilocybin addiction"
>Despite suggestive early findings on the therapeutic use of hallucinogens in the treatment of substance use disorders, rigorous follow-up has not been conducted. To determine the safety and feasibility of psilocybin as an adjunct to tobacco smoking cessation treatment we conducted an open-label pilot study administering moderate (20 mg/70 kg) and high (30 mg/70 kg) doses of psilocybin within a structured 15-week smoking cessation treatment protocol. Participants were 15 psychiatrically healthy nicotine-dependent smokers (10 males; mean age of 51 years), with a mean of six previous lifetime quit attempts, and smoking a mean of 19 cigarettes per day for a mean of 31 years at intake. Biomarkers assessing smoking status, and self-report measures of smoking behavior demonstrated that 12 of 15 participants (80%) showed seven-day point prevalence abstinence at 6-month follow-up. The observed smoking cessation rate substantially exceeds rates commonly reported for other behavioral and/or pharmacological therapies (typically <35%). Although the open-label design does not allow for definitive conclusions regarding the efficacy of psilocybin, these findings suggest psilocybin may be a potentially efficacious adjunct to current smoking cessation treatment models. The present study illustrates a framework for future research on the efficacy and mechanisms of hallucinogen-facilitated treatment of addiction.
>Pilot study of the 5-HT2AR agonist psilocybin in the treatment of tobacco addiction
>Matthew W Johnson, Albert Garcia-Romeu1, Mary P Cosimano and Roland R Griffiths (2014)
"psilocybin depression"
>Psilocybin was well tolerated by all of the patients, and no serious or unexpected adverse events occurred. The adverse reactions we noted were transient anxiety during drug onset (all patients), transient confusion or thought disorder (nine patients), mild and transient nausea (four patients), and transient headache (four patients). Relative to baseline, depressive symptoms were markedly reduced 1 week (mean QIDS diff erence –11·8, 95% CI –9·15 to –14·35, p=0·002, Hedges’ g=3·1) and 3 months (–9·2, 95% CI –5·69 to –12·71, p=0·003, Hedges’ g=2) after high-dose treatment. Marked and sustained improvements in anxiety and anhedonia were also noted.
>Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study
>Robin L Carhart-Harris, Mark Bolstridge, James Rucker*, Camilla M J Day*, David Erritzoe, Mendel Kaelen, Michael Bloomfi eld, James A Rickard, Ben Forbes, Amanda Feilding, David Taylor, Steve Pilling, Valerie H Curran, David J Nutt (2016)
And of course, there's a tremendous number of self-reports of this efficacy, to the extent that in tandem with the scientific support I would say it's reasonable to claim that it's common knowledge that psychs (the formal literature for LSD is more substantial than for shrooms, especially for addiction) help with depression and that psychs help with addiction. As someone who unwelcomely hangs around a board with raver cultural influences essentially a favela atmosphere, there's no way you haven't seen dozens of these accounts.

Kill yourself faggot
Replies: >>25310
and
>>25308
so this is clearly enough to say it's the most effective treatment by a country mile
let's not talk about schizophrenia or drug-induced psychosis/ptsd either
anyway glad it worked for you anon
Replies: >>25312
>>25310
>so this is clearly enough to say it's the most effective treatment by a country mile
The body of literature that these are literally the first search result of is, yes.
There are literally dozens of psilocybin studies and hundreds of psychedelic studies showing comparable or better results for addiction with likewise negligible side effects.
80% (!) versus <35% for SINGLE DOSE treatment vs. ongoing therapy (with and without prescribed medication) is "most effective by a country mile", yes.
>let's not talk about schizophrenia or drug-induced psychosis/ptsd either
Why, because there isn't any connection between those and clinical dose psilocybin or any evidence whatsoever of a contraindication or causal link respectively between those and LSD?
>anyway glad it worked for you anon
wew led
e
w
l
a
d

kill yourself faggot
jiru getting owned into the stratosphere lmaoooo
Replies: >>25319
>>25313
lol
there's more evidence that ketamine is useful for refractory depression than psilocybin btw if you want to argue that's a psychedelic
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>there's more evidence that ketamine is useful for refractory depression than psilocybin btw
Without looking into it I somewhat doubt that considering there's a lot for psilocybin (and it's an approved treatment for depression), but I have literally no awareness of ketamine in the literature. I guess it's not that surprising since it already has indications, so it's trivial to get studies for other conditions (and managing depression with pain-relief is a favorite pasttime of shrinks).

>and the other paper you cited depression is in treatment-resistant depression, which means they've already failed standard anti-depressant therapy
And? That's a total non-sequitur retard. I searched depression because it's topical and because I knew that there were studies on it and the point that I was contradicting was
>you know it's really not a good idea for people that aren't mentally healthy to do psychedelics right
Which has literally no evidence and which I gave a trivial example of as not even being considered as a potential complication in a trial of making people who aren't mentally healthy do psychedelics, and in which trial there was no consequence to making people who aren't mentally healthy do psychedelics.
It's neither common belief nor the scientific consensus that it's not a good idea to give psychedelics to people that aren't mentally healthy and trivial examination suggests that it's safe. If you want to dispute this then provide evidence, faggot.
>where even the author concludes it's a "potentially efficacious adjunct (added on to standard therapy) to current smoking cessation treatment models"
What the fuck does this have to do with anything? That's literally some faggot's official opinion in a journal under his real name for his real work when he has to hold on to his medical license. Even if he believed it, it's got literally nothing to do with the study, nor with the overall point.
Except he probably didn't even write it because you're paraphrasing the fucking abstract and if you read the actual discussion his position is basically 'conventional treatment sucks and we really need to investigate this option further'. But actually reading scientific literature is too hard for poor jiru.
>you clearly don't know what the fuck you are talking about and it's embarrassing
Yes, it's pretty embarrassing that you're this desperate in the face of
>top result
i.e. literally just spend five seconds looking and you'll find better evidence than this. Most of the studies which I'm paraphrasing from memory are late 2000s LSD studies but you can peruse the literature yourself to your own satisfaction. There are LSD studies from the fucking 60s on alcoholism with n > 120.
>if there was an overwhelming amount of evidence that it's superior to standard therapy it would already have plenty of professional advocacy, but there isn't because it's unfortunately a schedule 1 drug
There's overwhelmingly strong evidence that it's superior to standard therapy (and in any case, we're talking about a case that's resistant to standard therapy anyway). Indeed, psilocybin was literally approved as a breakthrough therapy in the USA in 2018 (for depression).
Yes, it's an illegal drug in most jurisdictions and that is a part of why there aren't as many studies on it as there should be. It's also of little to no pharmacological interest from a licensing perspective which is the bigger issue.
>i genuinely wish you were right but the evidence is still paltry
The scientific evidence is stronger than the evidence for most things that make it to the chemist by a factor of tens. Yes, it isn't voluminous, but it's both consistent (still waiting for you to name even one paper which contradicts anything I've said) and backed by an enormous number of non-clinical reports.

>i would be surprised if you could find even one randomized blinded trial
I'd be fucking surprised too.
I'll let you spend the half a second it'd take to figure out why instead of parroting words you aren't considering the meaning of, but we both know that's not going to happen is it?*

>please look though i'd like to know
If you'd like to know then why not look yourself faggot?

*And I was surprised, I found a dozen for depression in as many seconds
Here's a good one
>http://libgen.is/scimag/10.1177%2F0269881116675513
Since we both know you're allergic to either actually reading a study or thinking for half a second, I'll quote their summary of what I'm getting at
"Although double-blind methods are usually used to protect against such effects, expectancy is likely to be significantly operative in a standard drug versus placebo design when the drug being evaluated produces highly discriminable effects and participants and staff know the specific drug conditions to be tested."
Their solution was pretty cute though.

>deleting your posts
wew
I accept your concession
Replies: >>25323
>>25322
i deleted because it sounded cunty and i thought about blinding and realized that would be pointless
ketamine is already used in practice, which is another reason there's more evidence
here you go an NEJM published trial from 2021
https://pubmed.ncbi.nlm.nih.gov/33852780/
if you know anything about medical journals you know nejm is the best out there along with jama
they found no significant difference in antidepressant effect between psilocybin and escitalopram but it performed better in some of their secondary outcomes
that's actually really promising although definitely not enough to say it's the best therapy out there
i probably read more scientific literature than you do, unless it's something you're obligated to do too
did you really expect me to want to engage in an actual conversation with you when you're being so hostile
Replies: >>25332
so sure it's probably not be a bad idea especially if he's actually taken anti-depressants properly and for long enough without improvement
>It's literally the most effective treatment by a country mile
is still a stupid thing to say and i think you know that
not a bad idea*
are you that transbian pedo that thinks sex is disgusting
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>>25323
>here you go an NEJM published trial from 2021
<posts a paper literally showing psilocybin out-competing conventional therapy
Not sure what you're hoping to show here
>they found no significant difference in antidepressant effect between psilocybin and escitalopram but it performed better in some of their secondary outcomes
They declared a 33.33% improvement in the primary score not significant, sure.
>that's actually really promising although definitely not enough to say it's the best therapy out there
The statement that it's the best therapy out there was regarding addiction (there's scant research on dxm addiction, so I doubt you're going to find a psilocybin study), and the comparisons between conventional addiction treatments (<35%) and psychedelics (70-100% in everything I've seen) are a lot stronger, and the implication that this random paper is the entirety of the literature on the topic or even something that I referred to is fucking retarded.
>i probably read more scientific literature than you do
Let's be real, I probably read more scientific literature today than you do in a month. You didn't even finish reading the abstract of the paper you yourself cited.
<P=0.17
<We did not assess the effectiveness of blinding within each treatment group.
<most of the recruited volunteers referred themselves, and many expressed a preference for psilocybin over escitalopram. This created a selected trial population and limits generalization of the results.
<Also, average symptom severity scores at baseline were in the range for moderate depression, thus limiting extrapolations to patients with severe depressive symptoms or treatment-resistant depression.
Nice study retard
>did you really expect me to want to engage in an actual conversation with you
I genuinely doubt you're capable
>did you really expect me to want to engage in an actual conversation with you when you're being so hostile
lmao
Replies: >>25335
>>It's literally the most effective treatment by a country mile
>is still a stupid thing to say and i think you know that
Still waiting for even one scrap of evidence to the contrary
>>25332
>the implication that this random paper is the entirety of the literature on the topic or even something that I referred to
that's not what i was trying to imply at all
i don't know anything about it's use in sud and i can't be comprehensive because i have shit i need to do
so i'll take your word for it because i really don't give a fuck and you're probably correct
conventional addiction treatments of what? opiates and nicotine?
is it being compared to MAT and NRT+wellbutrin/chantix?
link me this one
>80% (!) versus <35% for SINGLE DOSE treatment vs. ongoing therapy (with and without prescribed medication) is "most effective by a country mile", yes
Replies: >>25338
>opiates and nicotine?
Alcohol (most common) and nicotine mostly.
Given that the established model for successful psychedelic treatments is analogous to cold turkey I wouldn't expect to see examples for any opiate where replacement therapy is indicated.
>is it being compared to MAT and NRT+wellbutrin/chantix?
"Yes". They're referring to the literature for expected outcomes from conventional treatment, for what should be obvious reasons. Very few studies are running trials of both because the structure of treatment is entirely different.
>so i'll take your word for it because i really don't give a fuck and you're probably correct
>i can't be comprehensive because i have shit i need to do
Yet you continued whining and lashing out long after >>25306, how curious
Replies: >>25340
>>25336
That was in reference to the study in the post you were replying to
>http://libgen.is/scimag/10.1177%2F0269881114548296
followup
>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641975/
Replies: >>25341
>>25337
the first study you cited as a top result looked like a whole lot of fucking nothing and then you went on talking about studies without actually providing any titles
"most effective by a country mile" sounded absurd so yes i assumed you were full of shit
>where replacement therapy is indicated
well that's basically always
>They're referring to the literature for expected outcomes from conventional treatment
for alcohol treatment really depends on severity but i'd expect them to compare it to acamprosate or naltrexone
disulfiram seems pretty dogshit
>>25338
i'll take a look at these later
Replies: >>25345
oh, it's the same one
do you really think a study with 15 people is adequate to say what you were saying?
it's right in title it's a pilot study
a study from the 60s would have been compared to not anything relevant now, so i would have to look at the others from the 2000s for alcohol
>>25341
get a job
Replies: >>25347 >>25354
why is he like this magick
i thought he has sex
Replies: >>25347 >>25348
>>25345
shut up
>>25346
looks go a long way i guess
>>25346
he doesn't have sex
Replies: >>25349
>>25348
you lie about everything so i must too right
Replies: >>25350
>>25349
he may not lie about everything
but he doesn't have sex
Replies: >>25351
>>25350
i don't lie about anything because i have no reason to, i don't e-date
i only defend myself i'm not trying to impress people and most of the time i clearly don't
lol
lole even
>>25345
I'm kinda surprised he's not a TA
He reminds me of this guy I used to work with who heated up bees for a h-index of like 3
Replies: >>25355
>>25354
i'm not a researcher or in academia, are you?
Replies: >>25356
>>25355
>i'm not a researcher
Aren't you a postgrad?
Do you have an internship lined up?
Replies: >>25357
>>25356
i'm clinical
i don't know how magick does this namefag shit it just feels bad, not sure how this could be healthy for anyone
>>25357
Take cocaine
>>25357
All the med students I knew were strippers unless you count the dentist
But I didn't know him that well so maybe he was a stripper too
>>25357
take cocaine
also you namefig irl, with your real name
so how do you do it then
also have sex, because you don't have sex
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Warmly waiting till I hear what
>let's not talk about schizophrenia or drug-induced psychosis/ptsd either
was supposed to be about.
Replies: >>25375 >>25377
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>>25374
he's just retarded and will say stupid stuff when cornered/nervous, don't stir him up
>>25374
what he said
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>go on the internet and DON'T be an obnoxious cunt
get real
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